Microscopy from Scientific Research

Close-up view of embryoids described in (C). The outermost panels represent a magnification of the corresponding image section marked with a rectangle. Filled arrowheads (full laminin assembly) indicate circumferential continuous, intact laminin (white) characterized by a well-defined laminin-cell interface (pink) and defined laminin compaction of different degrees (yellow). Open arrowheads (impaired laminin assembly) mark regions of discontinuous laminin (white) with a diffuse laminin-cell interface (pink) and a varying degree of less and irregular laminin compaction (yellow). Scale bars, 25 μm.

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