Scatter Plot from Scientific Research

A UMAP was generated for 1080 tumor samples (540 paired pre- and post-Tx samples) with euclidean metric for the set of 335 DEGs between pre-Tx and post-TX samples. As shown in (A), post-Tx samples (gray triangles) are separated from the pre-Tx samples (dots). Within the pre-Tx samples, there are three clearly separated groups: one small group of BasalL tumors (red) and two larger groups, each of them consisting of a mixture of LumA (dark blue) but also LumB (light blue) tumors. Therefore, this UMAP based classification is different from the traditional intrinsic subtypes.

DOI