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Schematic of conditional deletion of Mecp2 in 16-week old, adult Mecp2flox/y;UBC-CreERT2 mice using tamoxifen (TMX). Male mice were treated with 3× doses of either TMX (100 mg/kg) or peanut oil vehicle. TMX-treated animals are referred to as adult knockout (aKO) and shown in red, while vehicle-treated animals are referred to as control and shown in black.

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