Volcano Plot from Scientific Research

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Volcano plots of the fold change in mRNA expression (RNA-seq), ribosome occupancy (ribosome profiling), or ribosome occupancy normalized to mRNA levels (translational efficiency) plotted against the statistical significance of that change. Changes reflect changes in gene expression due to loss of eIF4E, for all genes passing automatic filtering in DESeq2. The vertical dashed line denotes a log2fold change (LFC) of 0, while the horizontal dashed line denotes an adjusted pvalue of 0.05. Genes that belong to the Gcn4 regulon are marked in red, while GCN4 is marked in blue.
#Volcano Plot#mRNA Expression#RNA-seq#Ribosome Occupancy#Ribosome Profiling#Translational Efficiency#Gene Expression#eIF4E#DESeq2#Gcn4 Regulon#GCN4
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