Illustration from Scientific Research

Graphical summary of purified His-MBP-tagged MYCN constructs. (+++) indicates the highest affinity RNA binding or highest sequence preference for a UG-rich (UGhigh) compared with UG-poor (UGlow) RNA oligonucleotide. MYCN protein domains are labeled on the full-length (FL) MYCN construct diagram. MB, MYC box; BR, basic region; HLH, helix-loop-helix; LZ, leucine zipper.

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