Protein Structure from Scientific Research

Structural analyses of the mature ADAM17/iRhom2 fusion. To show the flexible protease domain, the density map is also lowpass filtered and contoured at a lower threshold (white). On the right, the structure of the full-length ADAM17/iRhom2 complex is docked into the density to demonstrate the movement of the protease domain. For clarity, the prodomain structure is not shown.

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