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Quantifications of the western blots from three independent experiments of (D) using ImageJ. Error bars represent standard deviations (n= 3, three independent experiments). A Dunnett’s test is performed by computing a Student’s t statistic for each transfection condition compared with D475R+DMSO condition.*p< 0.0001,*p< 0.01; ns, not significant. Data are representative of three independent experiments (A–D). See alsoFigure S3.
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