Protein Structure from Scientific Research

Four major interfaces between iRhom2 and ADAM17 are highlighted. Selected residues comprising the interfaces (within 5 A distance) are shown in ball-and-stick representation. The ADAM17 prodomain is colored red, whereas the rest of ADAM17 is colored yellow. For highlighted side chains, we colored their oxygen atoms in red, nitrogen atoms in purple blue, and carbon atoms the same color as the main chain.

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