Line Plot from Scientific Research

2AP fluorescence assays comparing catalytically inactivated wild-type (WT-)GeoCas9 and iGeoCas9 R-loop kinetics (n= 3, data are represented as the mean SD). Substrate 1, early R-loop formation. Substrate 2, mid R-loop formation. Substrate 3, late R-loop formation. MgCl2 concentrations indicated above the graph. The rate constant kobs are listed in the sample legend. See also Figure S4C.

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