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Domain organization of GeoCas9. iGeoCas9 mutations indicated with red arrows. Deactivating mutations indicated with gray arrows. BH, bridge helix; WED, wedge; PI, PAM interacting; PLL, phosphate lock loop.
#Illustration#GeoCas9#iGeoCas9#Bridge Helix#Wedge#PAM Interacting Domain#Phosphate Lock Loop#Domain Organization#Mutation
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