Rupture tension as a function of rupture time. Data points acquired for different strain rates. The black dots show individual WT and the grey dots, individual K14-R125C monolayers. The coloured dots show the population average for a given strain rate. The whiskers indicate the standard deviation. The red and pink lines are linear regressions to the data. In the box plots, the central mark indicates the median, and the bottom and top of the box indicate the 25th and 75th percentiles, respectively. The whiskers extend to the most extreme data points that are not outliers. The data points are indicated by grey dots and the outliers, by red ‘+’ symbols. Statistics: two-sided Kolmogorov–Smirnov test, P < 0.01. Data from n = 10 WT, n = 9 K14-R125C, n = 11 NS and n = 12 DSP-shRNA monolayers.