Scatter Plot from Scientific Research

Distribution of the number of distinct ecDNA and ChrAmp amplicons by pretreatment status across primary, untreated advanced cancers and pretreated advanced cancer tumors. Pretreated advanced cancer tumors show a significantly higher number of distinct ecDNAs and ChrAmps per tumor compared to primary cancer or untreated advanced cancer tumors (two-sided MannWhitney U test). Y axis represents the number of distinct ecDNA and ChrAmp amplicons detected per tumor. Numbers indicate patient counts. All tumors with available pretreatment information were included in the analysis. Points represent mean values, and error bars show 95% CIs.

DOI