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The modified FX12 LNP formulation (FX12m, with lipid compositions indicated in the table) primarily edits the liver tissue with 37% efficiency. In vivo genome-editing levels in different tissues and different cell types in the liver were quantified by tdTom(+) signals using flow cytometry.
#Bar Plot#Error Bars#FX12 LNP Formulation#Liver Tissue#Genome Editing#Flow Cytometry#tdTom(+) Signals
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