Differential abundance of WM MS samples against control WM, as calculated by bootstrapped ANCOM-BC as in (H). Model fitted iscount ~lesion_type + sex + age_scale + pmi_cat. Abbreviations: WM, white matter; GM, gray matter; NAWM, normal-appearing white matter; NAGM, normal-appearing gray matter; AL, active demyelinated lesion; CAL, chronic active demyelinated lesion; CIL, chronic inactive demyelinated lesion; RL, remyelinated lesion; GML, gray matter demyelinated lesion.
