Top: Dataset 6 (large intestine, CODEX, specimen 1) containing a tissue fold (ROI, dashed white outline) as seen in channels SOX9 (colormap) and Hoechst (gray). Bottom: UMAP embedding of 57-channel single-cell data from the image above colored by SOX9 intensity (top left), ROI inclusion (top right) and HDBSCAN cluster (bottom center). Cluster 1 cells are those affected by the fold.
