Statistical comparison of ex vivo drug sensitivity differences in patient-derived PAX8+ cells between the treatments predicted by scTherapy to be either effective ( n = 18) or ineffective ( n = 10) in the individual patients ( p < 0.001, two-sided Wilcoxon test). Suppl. Fig. 7 shows the same data in a heatmap, summarizing the drug responses across multiple doses using drug sensitivity scores (DSS), instead of the percentage inhibition at the predicted effective dose (as shown here). Box plots show the median (central line), 25th and 75th percentiles (box edges), and the range within 1.5 times the interquartile range from the box (whiskers). Source data are provided as a Source Data file.
