(TOP) Schematic of experimental design: CAR-T cells were activated in the presence of glucose and then cultured in media +- glucose starting on day 4. Glucose concentration is 11 mM for all experiments unless otherwise noted. (BOTTOM) Viability and fold expansion on day 16. Pooled data of n = 2–4 donors. P values determined by paired two-tailed t -tests. Error bars represent SD.
