Heatmap from Scientific Research

Drug–target connectivity of select COSTAR-predicted drugs (columns; n = 23 COSTAR-HIT drugs; n = 25 COSTAR-NEG drugs) to primary and secondary drug targets (rows). COSTAR subscore (heatmap color scale) is the LASSO model coefficient multiplied by the integrated connectivity of drug to target mapping. Target genes with absolute COSTAR LASSO coefficients greater than 0.1 are displayed.

DOI