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Effects of PlaB on amounts of Tnf and Il1a pre-mRNA and mRNA in RAW macrophages expressing TTP-WT (as in B) and treated with PlaB (500 nM, 3.5 h). mRNA and pre-mRNA were assessed (RT-qPCR) and normalized to 36b4. Means and SDs, two-way ANOVAn =3*padj. < 0.05,**padj. < 0.01,***padj. < 0.001,****padj. < 0.0001.

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