Proximal interactome of WT-APX and NLSmut-APX in HEK-293 cells analyzed by LC-MS/MS. Induction of WT-APX, NLSmut-APX, and GFP-APX was carried out as in Figure 1B. (D) Overlap of WT-APX and NLSmut-APX interactomes. WT-APX and NLSmut-APX interactomes are defined as significantly enriched proteins (log2FC > 1,padj. ≤ 0.05,n =3) in differential enrichment analysis of WT-APX vs. GFP-APX and NLSmut-APX vs. GFP-APX, respectively.
