Validation of variant–ICD10 code associations in FinnGen Biobank (release 10 for ExWAS comparison and release 11 for GWAS comparison). FinnGen release 10 P values are from GWAS SAIGE 38 (two-sided, unadjusted) while release 11 P values are from GWAS REGENIE (two-sided, unadjusted). UKB ExWAS P values are from FET (two-sided, unadjusted) and UKB GWAS P values are from REGENIE–Firth (two-sided, unadjusted). Percentages with respect to imputed genotypes and mapped phenotypes with available FinnGen GWAS summary statistics file are given at the top of each bar plot. Box plots show the median as center line and top and bottom quartiles as box limits; whiskers extend to points within 1.5 interquartile ranges of the box limits; points denote outliers. No multiple testing correction was performed.
