Clustered from Scientific Research

Comparison of the expression profiles of HLF + SPINK2 + cells from HSPC clusters from PB1.1 BFP and RM TOM cells to reference data from human embryonic-derived and CB-derived endothelial and hematopoietic cell populations, using the ACTINN machine learning algorithm to determine the percentage of iPS cell-derived hematopoietic cells displaying the greatest similarity to each reference dataset. Data stratified by retinoid treatment are shown for each cell line. The bar height represents the percentage of HLF + SPINK2 + putative iHSCs that map most closely to each reference sample. Cell numbers mapping to each reference sample are shown in Supplementary Table 10 . EC, endothelial cell; VE, venous endothelium; AE, arterial endothelium; preHE, prehemogenic endothelium (representing aortic endothelium); HE, hemogenic endothelium; W, week; Plac, placenta; Ery, erythroid; Prog, progenitor; Meg, megakaryocyte; Mast, mast cell; Mono, monocyte; Mac, macrophage; Gran, granulocyte.

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