Workflow from Scientific Research

Schematic of the concept of single-cell trajectory alignment. The input is single-cell transcriptomic data of a reference and a query that change dynamically (left), for example, in vivo cell development and in vitro cell differentiation, control and drug-treated cells in response to perturbation, responses to vaccination or pathogen challenge in healthy and diseased individuals. Aligning the reference and query can capture matches and mismatches (middle), supporting further downstream analysis (right).

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