Illustration from Scientific Research

Phase separation behavior of GFP-tagged TDP-43 as a function of KCl concentration as observed by widefield microscopy imaging. The phase diagram (left panel) was generated from measurements at five KCl concentrations and at 0.5 µM protein concentration. Representative images at 100 mM and 25 mM KCl are shown (right panels). c crit denotes the critical KCl concentration. Experiments were repeated at least three times with similar results. Scale bar is 10 µm.

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