Immunofluorescence staining of HaCaT cells treated with Ctrl-IgG or PV-IgG and 5 M RGFP966 or 10 M Entinostat using DSG3, DSP antibodies and DAPI. Scale bar = 10 m. Quantification of DSG3 intensity/membrane length of 3 independent experiments are shown. Each data point represents one cell. PV-IgG DMSO vs Ctrl-IgG DMSO p = 0.0001, PV-IgG DMSO vs PV-IgG RGFP966 p < 0.0001, PV-IgG DMSO vs PV-IgG Entinostat p < 0.0002. Values are expressed as mean with standard deviation (mean +/-SD). One n represents one biological replicate. Source data are provided as a Source Data file. All experiments were statistically analyzed with One-way-ANOVA, SIDAK correction. p < 0.05*; p < 0.01**; p < 0.001***.
