Protein Structure from Scientific Research

N-terminal glycoproteins from BTV4. Linear representation of the BTV4 polyprotein displays location of putative glycosylation and the predicted signal peptidase cleavage sites that delineate five mature proteins (labelled A–E). For each of these mature proteins, the highest confidence models are shown from three prediction methods (ColabFold, ColabFold with custom MSAs and ESMFold). Protein B only yielded low-confidence models and is not shown. Each protein contains a putative transmembrane domain (pTMD), protein C contains a canonical furin cleavage site, and the conserved fusion loop (FL) of E is also annotated.

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