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RdRp phylogeny reveals three major lineages within the Flaviviridae : (1) Orthoflavivirus/jingmenvirus (including orthoflavivirus-like—for example, Tamana bat virus); (2) LGF/Pestivirus; and (3) Hepacivirus/Pegivirus. An unrooted tree is shown, with the tombusviruses (TOM) representing the outgroup taxa and a scale bar denoting the number of amino acid substitutions per site. Genome organization is provided for exemplar species, with annotations based on InterProScan searches.

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