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Schematic of the in vivo leukaemia model treated with type 2 low (ND585) or type 2 high (ND463) CAR T cells. NSG mice were i.v. injected with 1 x 10 6 Nalm6 cells. Then, 7 days later, mice were randomly assigned to three groups and were infused i.v. with 2 x 10 6 CAR T cells or PBS (control). The surviving mice were rechallenged with 1 x 10 6 Nalm6 cells 17 days after the CAR T infusion. The diagram was created using BioRender.
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