Levels of extracellular adenosine quantified by UPLC in the CSF collected from the cisterna magna of anesthetized ENT2-KO mice 30 min after exposure either to control light or 40 Hz light flickering for 30 min ( n = 5–7 mice/group, mean ± SEM in the bar graphs, * P < 0.05, ns, not significant, unpaired Student’s t -test).