Protein Structure from Scientific Research

Open access visualization of Protein Structure, Ubiquitin Chain Elongation, UBR4, UBL Domain, UBE2A
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Structural model of ubiquitin chain elongation by UBR4. The relative positions of the UBL domain of UBR4 (magenta), its bound ubiquitin (yellow), UBE2A with a charged ubiquitin, and a region of the UBR4 C-arm are shown. In this configuration, K48 (red spheres) of the UBL-bound ubiquitin is close to C88 of UBE2A (blue spheres) onto which ubiquitin is charged via its terminal glycine (G76). See also Figure S7.

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