Protein Structure from Scientific Research

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Structural model of ubiquitin chain elongation by UBR4. The relative positions of the UBL domain of UBR4 (magenta), its bound ubiquitin (yellow), UBE2A with a charged ubiquitin, and a region of the UBR4 C-arm are shown. In this configuration, K48 (red spheres) of the UBL-bound ubiquitin is close to C88 of UBE2A (blue spheres) onto which ubiquitin is charged via its terminal glycine (G76). See also Figure S7.
#Protein Structure#Ubiquitin Chain Elongation#UBR4#UBL Domain#UBE2A#Structural Model#Lysine-48#Glycine
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