Cumulative incidence plots for the indicated diseases and mortality for the top, median and bottom deciles of ProtAgeGap in the CKB (n = 3,977). The number of incident cases is shown for each disease, indicating the total number of incident cases only among individuals in the three deciles shown, not the full dataset. Incidence rates are shown for the subsequent 11-14 years (CKB) of follow-up after recruitment for each given age at recruitment (for example, in a the cumulative incidence rate shown at age 65 years is the rate of incident cases in the 11-16 years of follow-up for those aged 65 years at recruitment). All plots show the cumulative density of events at a given timepoint based on the Kaplan-Meier survival function, with 95% confidence intervals shown in lighter shading. Diseases shown here for the CKB are those with more than 10 cases across the three deciles of ProtAgeGap.