Scatter Plot from Scientific Research

Associations between ProtAgeGap and measures of physiological and cognitive function in the subsample of UKB participants with no lifetime diagnosis of any of the 26 diseases studied (n = 20,315). All models used linear or logistic regression and were adjusted for age, sex, Townsend deprivation index, recruitment center, ethnicity, IPAQ activity group and smoking status. In all plots, beta estimates (and 95% confidence intervals) for the association between ProtAgeGap and each outcome are shown on the x axis. Beta estimates in red are from the full 204-protein model (ProtAgeGap), whereas beta estimates in blue are from the smaller proteomic age clock model with 20 proteins (ProtAgeGap20). FEV 1 , forced expiratory volume in 1 s; IPAQ, International Physical Activity Questionnaire; FDR, false discovery rate.

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