Relative mRNA expression of clock genes Per1, Per2, Cry1, Cry2, Bmal1, Rorα, Rev-erb α, Rorβ normalized to s12 , ApoE and GAPDH in mPFC samples from naive mice injected at ZT00 with saline (control) and ketamine (KET) and harvested at ZT06 (6 h after injection), ZT18 (18 h after injection) and ZT06 (30 h post injection) ( n = 5 mice per group, two-way ANOVA with Bonferroni post hoc test: * P < 0.05, ** P < 0.01, *** P < 0.001 control vs. KET).