Relative mRNA expression of clock genes Per1, Per2, Cry1, Cry2, Bmal1, Rorα, Rev-erb α, Rorβ normalized to s12 , ApoE , and GAPDH in mPFC samples from CDM mice injected at ZT00 with saline (CDM) or ketamine (KET) and harvested every 4 h from ZT06 (6 h after injection) till ZT06 (30 h post injection) ( n = 5 mice per group, two-way ANOVA: P values of the CDM effect is displayed inside the graph, Bonferroni post hoc test: * P < 0.05, ** P < 0.01, *** P < 0.001 CDM vs. KET).
