Graphs show cytosolic Ca 2+ change measurements stimulated by CCh with fura2 fluorescence (340/380). A representative trace from three independent experiments shows calcium reabsorption is decreased in DKO, and the graph shows the average of the group responses. Cells analyzed for calcium release studies are WT = 138 and DKO = 122 cells, and for calcium release WT = 136 and DKO = 122 cells. Error bars: SM. Unpaired two-tailed t -test; * p = 0.0309.