Incidence rates among subgroups following administration of mRNA-1273 as a 50-µg booster dose are presented. Error bars represent 95% confidence intervals. Incidence is defined as the number of participants with an event starting 14 days after booster by the number of participants at risk at 14 days after booster and adjusted by person-months (total time at risk) in each treatment group. 1 month = 30.4375 days. White is defined as White and non-Hispanic, and communities of color include all the others whose race or ethnicity is unknown, unreported, or missing. Participants at risk for severe COVID-19 included those aged 65 years and <65 years with at least one of the risk factors (chronic lung disease, significant cardiac disease, severe obesity, diabetes, liver disease, or HIV infection). CI confidence interval, COVID-19 coronavirus disease 2019, IR incidence rate, N number of participants at risk.