Illustration from Scientific Research

Open access visualization of Illustration, NHL-1, CRISPR-Cas9, E3 ligase
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DOI: 10.1038/s41467-024-51069-3

DOI

The nhl-1(syb8175) strain was generated by exchanging the first two conserved cysteine residues in the N-terminal Really Interesting New Gene (RING) domain of NHL-1 to alanines by CRISPR-Cas9 (p.C43A;C46A) effectively abolishing its E3 ligase activity.

#Illustration#NHL-1#CRISPR-Cas9#E3 ligase

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