Bar Plot from Scientific Research

Binding affinity of the RBD of SARS-CoV-2 S proteins to ACE2 by yeast surface display. The dissociation constant (KD) value indicating the binding affinity of SARS-CoV-2 S RBD to soluble ACE2 when expressed on yeast is shown. Each dot indicates the result of an individual replicate. The dashed horizontal lines indicate the value of BA.2. Statistically significant differences versus each parental S protein and those between BA.2 were determined by two-sided students’ t tests.

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