Michaelis Menten parameters (K M and k cat ; light and dark grey) for the proteolytic degradation of Suc-AAPF-pNA catalysed by aCt, aCt cPA conjugate, B 1 (aCt) or B 6 (aCt). The data are presented as mean s.d. from n = 2 or 3 biological replicates (Supplementary Table 3 ). The whiskers (in h and i ) are 1.5 s.d.; mean (white dots) and median (black lines) are indicated for each data set. No outliers have been excluded.