Workflow from Scientific Research

Binding of the uNK cell cytokines to receptors on EVTs triggers multiple effects including regulating the availability of growth factors, dampening inflammation, enhancing EVT differentiation, and influencing blood flow. VCT, villous cytotrophoblast; SCT, syncytiotrophoblast; iEVT, interstitial EVT; eEVT, endovascular EVT; macro, macrophages; PV, perivascular cells; endo, endothelial cells; EMT, epithelial-mesenchymal transition; IGF, insulin-like growth factor; IGFBP, insulin-like growth factor binding protein.

DOI