Selected molecular changes induced by the uNK cell cytokines, with their expression patterns in in vivo EVTs collected from decidua (red) and CCC (blue) shown in the first two columns and different EVT subtypes from organoids treated with (orange) and without (purple) cytokines in the following columns. The last column shows the expression of these genes in EVTs from pre-eclamptic (magenta) and normal (green) placentas. Genes marked by asterisks are significantly downregulated in pre-eclamptic EVTs (BH-corrected p value < 0.05). CCC, cytotrophoblast cell column; PE, pre-eclampsia; EMT, epithelial-mesenchymal transition.
