Heatmap from Scientific Research

Hi-C contact frequency signatures for three SV types (deletions, duplications, inversions). Signatures were defined by subsetting Hi-C contact frequencies in a 600-kb search space around each known SV detected using WGS, centered around the two breakpoints of the SV. The individual Hi-C submatrices for each SV in each sample were then averaged across each of the SV types (top) and compared to the size-matched background, where random regions of the same size as the SVs were visualized using the same approach as for the SVs (bottom).

DOI