Median-centered log-ratio of Hi-C contact frequency comparing mCRPC samples and benign prostate. TMPRSS2 – ERG fusion-positive samples (with breakpoints within five bins of the median) above the diagonal (canonical TMPRSS2 – ERG fusion was defined using WGS, all but one consistent with monoallelic deletion, with one complex rearrangement) and negative below it. Green, higher in mCRPC; blue, higher in benign prostate.
