For SNVs observed in tumors, lower function scores correlate with more independent observations in cBioPortal (n = 233 SNVs, Spearman’s = -0.25, two-sided P = 9.7 x 10 -5; = -0.58, P = 2.7 x 10 -22 when analysis restricted to n = 172 SNVs seen in ccRCC).
