Fraction of the variance in mRNA expression explained by each of the four variables on the y axis as follows: y = ASM-QTL represents the genotype of the ASM-QTL found in association with 5-mCpG rates of MDSs; y = 5-mCpG represents the 5-mCpG rates of MDSs; y = 5-mCpG|ASM-QTL represents the 5-mCpG rates of MDSs after correction for the ASM-QTL found in association with that same MDS; y = ASM-QTL|5-mCpG represents the genotype of the ASM-QTL found in association with 5-mCpG rates of MDSs after having corrected the genotype status for the 5-mCpG rates of that same MDS. In both b and c , the center line (solid black) shown in each box represents the median; box limits represent upper and lower quartiles; whiskers represent 1.5 interquartile range. r 2 mRNA,5-mCpG in b is equivalent to the reversed comparison of r 2 5-mCpG,mRNA in c .
