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Architecture of ASIP isoforms and composition of the SVA F 1 retrotransposon insertion. ASIP has four known alternate first exons (dark blue), with the first three (exons 1A, 1B and 1C) able to either splice directly to a coding exon (gold; exon 3) or first to an additional 5 UTR exon (light blue; exon 2). The SVA F 1 insertion contains the expected 5 truncation with MAST2 exon followed by VNTR and SINE-R sequences. The location of the SVA F 1 insertion, present in the GRCh38 reference, is indicated by the purple thin vertical bar.

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