Chemical Structure from Scientific Research
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To demonstrate the viability of the CPG solid support, 5x N + 5 oligonucleotides were enzymatically synthesized in a stir reactor format. Their sequences comprised natural and modified bases, with one partially modified with 2'-fluoro groups and another fully modified with both 2'-fluoro and 2'-methoxy groups.
#Chemical Structure#CPG Solid Support#Oligonucleotides#Enzymatic Synthesis#Modified Bases#Stir Reactor
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