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Design of the cis -acting editing reporter and illustration of the applied triplet base-pairing motifs. The orientation of wobble base pairs at nearest neighbor positions or the presence of G or C counter bases modulate -editing at the central A of a triplet in comparison to its fully WatsonCrick base-paired counterpart. All triplet base-pairing motifs with ocher background color were installed at the empty dotted outline within the cis -acting editing construct to generate the results in b , c .

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