Scatter Plot from Scientific Research

Schematic of the human genome-wide TCR-MAP screen of the IG4 TCR + SrtA-Jurkats and peptide enrichment results. The 90-aa peptides tiled across the human proteome with 22-aa overlap were expressed in HLA-A*02:01 + G 5 -target cells. Each dot represents one peptide, with the y axis plotting the -log 10 adjusted P values determined by Mageck and the x axis indicating the geometric mean of the enrichment of the peptide across three replicates. Fold enrichment is defined as the ratio of the abundance of the peptide in the sorted population relative to the input library. Peptides highlighted in red contain the known epitope sequence for the IG4 TCR.

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