Volcano Plot from Scientific Research

Differences between conformations: wild type versus the 77-GA mutant. Comparison of ratios between top and bottom expression quantiles for the two cell lines. Higher values on the x axis indicate that sgRNAs targeting this gene have a stronger effect on reporter gene expression in the reference cell line compared with the 77-GA mutant cell line. Top: ratio of ratios comparison 57 represented as a volcano plot. Genes are colored as in a . Bottom: GSEA plot for the NMD pathway for the above comparison. logP: negative logarithm of P value.

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